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Engineered bone with purposeful marrow. Credit score: Varghese lab, UC San Diego Engineers on the College of California San Diego have developed biomimetic bone tissues that might in the future present new bone marrow for sufferers needing transplants. Bone marrow transplants are used to deal with sufferers with bone marrow illness. Earlier than a transplant, a affected person is first given doses of radiation, generally together with medicine, to kill off any current stem cells within the affected person's bone marrow. This pre-treatment is supposed to enhance success of the transplant by clearing up area within the marrow, permitting donor cells to outlive and develop with out competitors from the affected person's personal cells. However this therapy usually comes with dangerous negative effects, resembling nausea, fatigue, lack of fertility and others. To deal with these points, a crew led by bioengineering pr...

The nostril is lined with sensory tissue, the olfactory epithelium, that incorporates numerous kinds of cells, all of which come up from olfactory stem cells (inexperienced). Amongst these are smell-sensing neurons (orange), progenitor cells (cyan) and help cells (magenta sustentacular cells and blue microvillous cells). Credit score: Russell Fletcher & John Ngai, UC Berkeley Grownup stem cells have the power to remodel into many kinds of cells, however tracing the trail particular person stem cells observe as they mature and figuring out the molecules that set off these fateful choices are tough in a dwelling animal. College of California, Berkeley, neuroscientists have now mixed new strategies for sequencing the RNA in single cells with detailed statistical evaluation to extra simply monitor particular person stem cells within the nostril, uncovering clues that sometime might assist restore odor to those that have mispl...